Abstract: To deeply explore the impact and empowerment of artificial intelligence (AI) large models on the innovative development of industrial engineering, this paper first briefly introduces the historical integration of industrial engineering and AI, analyzing the challenges and opportunities faced by industrial engineering in addressing complex problems in manufacturing and service systems in the era of AI large models. Then, the current applications of AI large models in industrial engineering are introduced, including their innovative applications in manufacturing, supply chain management, and service industries. The future trends in the implementation of AI large models in the industrial engineering are also discussed. Finally, the paper proposes several suggestions for talent training in industrial engineering empowered by AI, emphasizing the importance of innovative thinking and practical skills.