Abstract: The concept of multi-cell system facility layout is introduced. The hybrid facility layout problem is converted into a multi-cell system layout design problem. Fuzzy theory is used to divide facility system into multi-cell facility system. The “field” fractal theory is used to design the most optimized layout for intra-cell layout and cellular layout. Numerical examples demonstrate that, without limiting to the form of hybrid facility layout, the proposed method can solve the hybrid facility layout problem well. It may serve as theoretical reference for similar researches.