Abstract: For titanium dioxide production, the effect of the latest advanced technological combination in sulfuric acid method on economic benefit is discussed in this paper. The problem is formulated as an inputoutput model by considering environmental protection and cost. Then, the effect of the advanced technological combination on economic benefits of the byproducts, the cost savings of “three wastes”, and the reduction of environmental cost are analyzed. Results show that the proposed Input-Output model is applicable to the production of sulfuric acid process. Also, it shows that the technological combination is feasible and operational.