Abstract: For emergency logistics management, decision making of supply distribution facility location is important. According to the uncertainties in emergencies, a two-stage robust optimization model for emergency facility location problems to achieve coordination between "pre-location" and "re-location" is proposed. In the first stage when demand, cost and facility disruption is uncertain, in the consideration of different needs of pre-disaster planning, post-disaster response and facility re-location, a robust "pre-location" model is presented based on p-center model. In the second stage, with the acquisition of post-disaster information, a "re-location" model for building new facilities is presented based on reactive repairing and adjustment for previous strategies. A numerical study shows the model is more effective than traditional p-center model for emergency facility location.