Abstract: In order to reduce the cost of manufacturing and service for cloud clients, solve the problem of resources optimization deployment for no need preference under the circumstance of cloud manufacturing, take into full consideration the interests of enterprises which need manufacturing resources and cloud platform operators, together with QoS and flexibility of both sides in the process of manufacturing resources configuration service, a multi-objective optimization model is built for resource allocation. This model represents interests of the above-mentioned two parties. In addition, the model examples are solved by modifying NSGA-Ⅱ algorithm. Results prove that the model and the algorithm are feasible, effective and stable.